NAA10

Across TCGA pan-cancer cohorts, NAA10 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NAA10 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NAA10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NAA10 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

CCRCC, GBM, and UCEC are the cancer types where NAA10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.367	1.000	<.001	36	view →
GBM	OS	Tertile	All	0.706	0.867	.015	19	view →
UCEC	OS	Median	III,IV	1.000	0.433	.007	12	view →
LSCC	OS	Median	II,III,IV	1.000	0.885	.021	5	view →
LUAD	OS	Median	II,III,IV	0.442	0.899	.015	5	view →
HNSC	DFS	Tertile	III,IV	0.710	0.880	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NAA10–CCRCC (DFS)

Open the CCRCC breakdown →