N6AMT1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, N6AMT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated N6AMT1 data layer compared with 20 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher N6AMT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated N6AMT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where N6AMT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSTertileIII,IV0.4590.822.01216view →
PDACOSMedianII,III,IV0.3730.596.0235view →
UCECDFSMedianIII,IV0.4600.889.0444view →
HNSCDFSQuartileIV1.0000.802.0482view →
GBMOSTertileAll0.7920.935.0291view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

N6AMT1–CCRCC (DFS)

Kaplan–Meier survival curve for N6AMT1 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration