N4BP3

Across TCGA cell cohorts, N4BP3 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible N4BP3-associated genes across cancer lineages are C9orf92, KCNK17, and REG1B. Each is linked with N4BP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both N4BP3-to-partner and partner-to-N4BP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C9orf92 grouped by N4BP3-low versus N4BP3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP3→partner) and Y-score (partner→N4BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	C9orf92 →	+0.108	+5.000	.003	.006	3	1
LARGE_INTESTINE	KCNK17 →	+0.058	+2.906	<.001	.007	3	1
LARGE_INTESTINE	REG1B →	+1.687	+2.933	.003	.003	3	1
LARGE_INTESTINE	OR10W1 →	+0.013	+3.977	<.001	<.001	3	1
LARGE_INTESTINE	ACSM6 →	+0.016	+3.000	.005	.005	3	1
LARGE_INTESTINE	FAM205A →	+0.023	+3.029	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

C9orf92 by N4BP3 expression — PANCREAS

Explore this box plot interactively →