N4BP2L1

Across TCGA patient cohorts, N4BP2L1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,717 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible N4BP2L1-associated genes across cancer lineages are LDHA, CXCL8, and RAP1AP. Each is linked with N4BP2L1 in more than 3 cancer types. Because this analysis shows association rather than direction, both N4BP2L1-to-partner and partner-to-N4BP2L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, N4BP2L1 versus LDHA in HNSC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2L1→partner) and Y-score (partner→N4BP2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LDHA →	-1.006	-0.617	<.001	<.001	3	4
HNSC	CXCL8 →	-2.413	-0.688	.006	.005	3	4
HNSC	RAP1AP →	+1.040	+0.614	.002	.002	3	4
OV	TTC16 →	+0.576	+0.419	.004	.004	2	4
HNSC	ADAM28 →	+1.558	+0.920	.001	<.001	3	3
LUAD	RDH11 →	-0.486	-0.363	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,717 associations by consensus.

N4BP2L1 vs LDHA — HNSC

Explore this scatter interactively →