N4BP2L1

Across TCGA patient cohorts, N4BP2L1 mutation is significantly associated with the RNA expression of many other genes, with 856 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible N4BP2L1-associated genes across cancer lineages are RNA5SP419, SNX18P23, and MIR4774. Each is linked with N4BP2L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both N4BP2L1-to-partner and partner-to-N4BP2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by N4BP2L1-low versus N4BP2L1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2L1→partner) and Y-score (partner→N4BP2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP419 →	+0.723	+5.517	<.001	.001	3	3
READ	SNX18P23 →	+0.078	+5.653	<.001	.003	3	2
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
UCEC	RN7SL134P →	+0.102	+2.221	.006	.008	3	2
LUSC	PRAMEF7 →	+0.055	+4.496	<.001	.007	3	2
LUSC	RNA5SP420 →	+0.690	+4.724	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 856 associations by consensus.

RNA5SP419 by N4BP2L1 expression — LUSC

Explore this box plot interactively →