N4BP2

Across TCGA patient cohorts, N4BP2 mutation is significantly associated with the RNA expression of many other genes, with 2,685 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible N4BP2-associated genes across cancer lineages are RNA5SP164, OR5AN1, and CENPM. Each is linked with N4BP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both N4BP2-to-partner and partner-to-N4BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP164 grouped by N4BP2-low versus N4BP2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2→partner) and Y-score (partner→N4BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP164 →	+0.078	+4.351	<.001	.003	3	3
PRAD	OR5AN1 →	+0.044	+6.748	<.001	<.001	3	3
UCEC	CENPM →	+0.563	+1.669	<.001	<.001	3	3
UCEC	OIP5 →	+0.569	+2.137	<.001	<.001	3	3
UCEC	C1QBP →	+0.403	+2.435	.001	<.001	3	3
UCEC	MRPS2 →	+0.358	+2.885	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,685 associations by consensus.

RNA5SP164 by N4BP2 expression — BLCA

Explore this box plot interactively →