N4BP2

Across TCGA cell cohorts, N4BP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,878 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible N4BP2-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of double-strand break repair, and Positive regulation of DNA recombination. Each is linked with N4BP2 in more than 18 cancer types. Because this analysis shows association rather than direction, both N4BP2-to-partner and partner-to-N4BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by N4BP2-low versus N4BP2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2→partner) and Y-score (partner→N4BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.085	+1.179	<.001	<.001	3	19
BONE	Positive regulation of double-strand break repair →	+0.101	+1.063	<.001	<.001	3	18
BONE	Positive regulation of DNA recombination →	+0.140	+1.355	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA repair →	+0.076	+0.981	<.001	<.001	3	17
BONE	Positive regulation of monoatomic ion transport →	-0.139	-1.057	<.001	<.001	3	17
BLOOD_Lymphoma	Regulation of RNA stability →	+0.055	+0.890	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,878 associations by consensus.

Positive regulation of DNA repair by N4BP2 expression — BONE

Explore this box plot interactively →