N4BP2

Across TCGA cell cohorts, N4BP2 mutation is significantly associated with the mutation status of many other genes, with 6,854 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible N4BP2-associated genes across cancer lineages are PLXNA2, MECOM, and BCLAF1. Each is linked with N4BP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both N4BP2-to-partner and partner-to-N4BP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PLXNA2 grouped by N4BP2-low versus N4BP2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2→partner) and Y-score (partner→N4BP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PLXNA2 →	+3.257	+4.362	.005	.005	1	5
STOMACH	MECOM →	+4.025	+2.942	.009	.009	1	5
LARGE_INTESTINE	BCLAF1 →	+2.602	+1.913	<.001	<.001	1	5
BLOOD_Leukemia	UNKL →	+3.343	+3.125	<.001	<.001	1	5
BLOOD_Lymphoma	NHS →	+3.754	+3.025	.006	.006	1	5
LUNG_NSCLC_LUAD	MAGI2 →	+2.981	+3.266	.009	.009	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,854 associations by consensus.

PLXNA2 by N4BP2 expression — PANCREAS

Explore this box plot interactively →