N4BP1

Across TCGA patient cohorts, N4BP1 mutation is significantly associated with the RNA expression of many other genes, with 3,523 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible N4BP1-associated genes across cancer lineages are RNVU1-28, RN7SL478P, and FOXL3. Each is linked with N4BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both N4BP1-to-partner and partner-to-N4BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNVU1-28 grouped by N4BP1-low versus N4BP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP1→partner) and Y-score (partner→N4BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNVU1-28 →	+0.498	+1.474	<.001	.002	3	2
UCEC	RN7SL478P →	+0.129	+1.354	.007	.008	3	2
LIHC	FOXL3 →	+0.077	+4.618	<.001	.001	3	2
UCEC	ZNF511 →	+0.288	+2.436	.005	.001	3	2
UCEC	PPP1R14C →	-1.029	-1.574	<.001	.002	3	2
UCEC	IGHD2-15 →	+0.984	+1.374	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,523 associations by consensus.

RNVU1-28 by N4BP1 expression — UCEC

Explore this box plot interactively →