N4BP1

Across TCGA cell cohorts, N4BP1 mutation is significantly associated with the RNA expression of many other genes, with 409 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible N4BP1-associated genes across cancer lineages are DTHD1, C18orf63, and CBY1. Each is linked with N4BP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both N4BP1-to-partner and partner-to-N4BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DTHD1 grouped by N4BP1-low versus N4BP1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP1→partner) and Y-score (partner→N4BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DTHD1 →	+0.056	+5.087	<.001	.004	3	1
BLOOD_Lymphoma	C18orf63 →	+0.012	+4.867	<.001	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.822	+3.459	<.001	.001	3	1
LARGE_INTESTINE	SGSM3 →	+0.654	+3.364	.006	.002	3	1
LARGE_INTESTINE	SLC25A17 →	+0.705	+3.169	<.001	.009	3	1
LARGE_INTESTINE	RBFA →	+0.767	+3.364	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 409 associations by consensus.

DTHD1 by N4BP1 expression — URINARY_TRACT

Explore this box plot interactively →