MZT2A

Across TCGA patient cohorts, MZT2A protein abundance is significantly associated with the protein abundance of many other proteins, with 7,577 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MZT2A-associated proteins across cancer lineages are SRRM2_S2044, CTNNB1_S191, and HMG20A_S105. Each is linked with MZT2A in more than 2 cancer types. Because this analysis shows association rather than direction, both MZT2A-to-partner and partner-to-MZT2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MZT2A versus SRRM2_S2044 in PDAC, with a Pearson correlation of -0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MZT2A→partner) and Y-score (partner→MZT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SRRM2_S2044 →	-0.925	-0.338	.003	<.001	3	3
PDAC	CTNNB1_S191 →	-1.795	-0.369	<.001	<.001	3	3
PDAC	HMG20A_S105 →	-1.086	-0.374	.001	<.001	3	2
LUAD	KDM4C →	+0.876	+1.095	<.001	<.001	3	2
BRCA	MAP1S_S481 →	-1.754	-0.412	<.001	.004	3	2
PDAC	AP2B1 →	-0.585	-0.483	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,577 associations by consensus.

MZT2A vs SRRM2_S2044 — PDAC

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