MZT2A

Across TCGA cell cohorts, MZT2A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MZT2A-associated genes across cancer lineages are SLC5A7, ODF4, and FABP12. Each is linked with MZT2A in more than 1 cancer types. Because this analysis shows association rather than direction, both MZT2A-to-partner and partner-to-MZT2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A7 grouped by MZT2A-low versus MZT2A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MZT2A→partner) and Y-score (partner→MZT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC5A7 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	ODF4 →	+0.057	+4.922	<.001	.009	3	1
BLOOD_Leukemia	FABP12 →	+0.054	+5.201	.008	.006	3	1
BLOOD_Leukemia	PRAMEF19 →	+0.022	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SLC5A7 by MZT2A expression — BLOOD_Leukemia

Explore this box plot interactively →