MZB1

Across TCGA patient cohorts, MZB1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,523 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MZB1-associated genes across cancer lineages are PIM2, CD79A, and POU2AF1. Each is linked with MZB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MZB1-to-partner and partner-to-MZB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MZB1 versus PIM2 in LSCC, with a Pearson correlation of 0.86.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MZB1→partner) and Y-score (partner→MZB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIM2 →	+1.438	+1.049	<.001	<.001	3	10
OV	CD79A →	+2.522	+1.824	<.001	<.001	3	10
HNSC	POU2AF1 →	+1.690	+1.112	<.001	<.001	3	10
HNSC	AMPD1 →	+0.935	+0.617	<.001	<.001	3	10
LSCC	LAX1 →	+1.616	+1.151	<.001	<.001	3	10
OV	JCHAIN →	+3.540	+1.515	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,523 associations by consensus.

MZB1 vs PIM2 — LSCC

Explore this scatter interactively →