MYZAP

Across TCGA patient cohorts, MYZAP mutation is significantly associated with the RNA expression of many other genes, with 1,195 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYZAP-associated genes across cancer lineages are RNA5SP410, DEFB108D, and BSNDP3. Each is linked with MYZAP in more than 2 cancer types. Because this analysis shows association rather than direction, both MYZAP-to-partner and partner-to-MYZAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP410 grouped by MYZAP-low versus MYZAP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYZAP→partner) and Y-score (partner→MYZAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP410 →	+0.509	+2.151	<.001	<.001	3	3
HNSC	DEFB108D →	+0.204	+7.954	<.001	.008	3	2
HNSC	BSNDP3 →	+0.129	+7.954	<.001	.008	3	2
UCEC	FLVCR1-DT →	+0.399	+2.258	.004	.001	3	2
UCEC	RNA5SP248 →	+0.321	+1.956	<.001	.001	3	2
UCEC	HMGN2P32 →	+0.372	+2.195	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,195 associations by consensus.

RNA5SP410 by MYZAP expression — UCEC

Explore this box plot interactively →