MYZAP

Across TCGA cell cohorts, MYZAP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,705 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible MYZAP-associated GO terms across cancer lineages are Biological process involved in interaction with host, Regulation of actin polymerization or depolymerization, and Negative regulation of actin filament polymerization. Each is linked with MYZAP in more than 11 cancer types. Because this analysis shows association rather than direction, both MYZAP-to-partner and partner-to-MYZAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Biological process involved in interaction with host grouped by MYZAP-low versus MYZAP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYZAP→partner) and Y-score (partner→MYZAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Biological process involved in interaction with host →	+0.099	+1.764	.003	.006	3	12
PANCREAS	Regulation of actin polymerization or depolymerization →	+0.101	+2.134	.001	<.001	3	10
PANCREAS	Negative regulation of actin filament polymerization →	+0.159	+2.319	.001	<.001	3	10
URINARY_TRACT	Response to steroid hormone →	+0.080	+2.079	<.001	<.001	3	10
PANCREAS	Regulation of actin filament length →	+0.102	+2.248	.001	<.001	3	10
URINARY_TRACT	Negative regulation of supramolecular fiber organization →	+0.098	+2.736	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,705 associations by consensus.

Biological process involved in interaction with host by MYZAP expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →