MYZAP

Across TCGA cell cohorts, MYZAP mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible MYZAP-associated genes across cancer lineages are C18orf63, RBP3, and ACER1. Each is linked with MYZAP in more than 1 cancer types. Because this analysis shows association rather than direction, both MYZAP-to-partner and partner-to-MYZAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C18orf63 grouped by MYZAP-low versus MYZAP-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYZAP→partner) and Y-score (partner→MYZAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	C18orf63 →	+0.013	+4.807	<.001	.006	3	1
BLOOD_Myeloma	RBP3 →	+0.006	+4.807	<.001	.006	3	1
LARGE_INTESTINE	ACER1 →	+0.111	+3.823	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

C18orf63 by MYZAP expression — BLOOD_Myeloma

Explore this box plot interactively →