Across TCGA pan-cancer cohorts, MYT1L-AS1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MYT1L-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MYT1L-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MYT1L-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

UCEC, LGG, and COAD are the cancer types where MYT1L-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.834	0.930	.002	90	view →
LGG	DFS	Median	All	0.489	0.297	<.001	46	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
LAML	DFS	Tertile	All	0.111	0.586	<.001	36	view →
THCA	DFS	Tertile	III,IV	0.145	0.765	.003	27	view →
UVM	OS	Tertile	All	0.220	0.917	<.001	27	view →
SKCM	DFS	Tertile	III,IV	0.119	0.601	<.001	21	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	18	view →
KIRC	DFS	Tertile	All	0.746	0.869	.018	18	view →
DLBC	OS	Tertile	All	0.053	0.936	<.001	18	view →
HNSC	DFS	Tertile	III,IV	0.340	0.623	.029	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

Exploration

Same gene, other analysis: MYT1L-AS1 tumor-vs-normal RNA expression · all MYT1L-AS1 data types