MYSM1

Across TCGA pan-cancer cohorts, MYSM1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of MYSM1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MYSM1 RNA is repressed in tumor relative to normal tissue. In most cancer types MYSM1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, BLCA, and LIHC are the cancer types where MYSM1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYSM1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.426	.001	8	view →
BLCA	Female	III,IV	+0.552	.001	7	view →
LIHC	All	All	+0.510	<.001	6	view →
CHOL	All	All	+1.896	<.001	5	view →
KICH	All	All	−0.635	.001	4	view →
HNSC	Female	III,IV	+0.810	.016	3	view →
PRAD	All	All	+0.412	.004	2	view →
KIRC	All	All	+0.211	.025	2	view →
ESCA	Female	All	+0.523	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

MYSM1–THCA

Open the THCA breakdown →