MYRF-AS1

Across TCGA pan-cancer cohorts, MYRF-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MYRF-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MYRF-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MYRF-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

LUAD, COAD, and LUSC are the cancer types where MYRF-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.183	0.424	<.001	116	view →
COAD	OS	Median	II,III,IV	0.645	0.877	<.001	99	view →
LUSC	OS	Tertile	II,III,IV	0.422	0.665	<.001	92	view →
KIRP	DFS	Tertile	All	0.635	0.876	<.001	78	view →
UCS	DFS	Quartile	II,III,IV	0.786	0.219	.002	60	view →
KICH	DFS	Tertile	III,IV	0.053	0.789	<.001	51	view →
HNSC	OS	Quartile	IV	0.811	0.574	.001	24	view →
BLCA	OS	Quartile	All	0.500	0.727	.005	20	view →
ACC	OS	Tertile	IV	0.344	0.724	.038	15	view →
KIRC	DFS	Tertile	IV	0.663	0.210	.012	12	view →
UVM	DFS	Tertile	All	0.485	0.858	.006	12	view →
ESCA	OS	Median	All	0.617	1.000	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MYRF-AS1–LUAD (DFS)

Open the LUAD breakdown →