MYOZ3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYOZ3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,765 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MYOZ3-associated genes across cancer lineages are SNRPD3, SHD, and PDE1B. Each is linked with MYOZ3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYOZ3-to-partner and partner-to-MYOZ3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYOZ3 versus SNRPD3 in LSCC, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOZ3→partner) and Y-score (partner→MYOZ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCSNRPD3 →-0.600-0.613.007.00132
HNSCSHD →+0.871+1.232<.001<.00132
LSCCPDE1B →+0.472+0.640.001<.00132
LSCCAGAP2 →+0.562+0.579.003.00232
HNSCJPH2 →+1.286+1.274<.001<.00132
HNSCPI16 →+1.146+0.831<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,765 associations by consensus.

MYOZ3 vs SNRPD3 — LSCC

Per-sample scatter of MYOZ3 vs SNRPD3 in LSCC (Pearson r = -0.54).

Explore this scatter interactively →

Exploration