MYOZ3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MYOZ3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,204 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYOZ3-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Cytoplasmic translation, and Negative regulation of myoblast fusion. Each is linked with MYOZ3 in more than 10 cancer types. Because this analysis shows association rather than direction, both MYOZ3-to-partner and partner-to-MYOZ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by MYOZ3-low versus MYOZ3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOZ3→partner) and Y-score (partner→MYOZ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaNegative regulation of syncytium formation by plasma membrane fusion →+0.079+0.174<.001.004311
OVARYCytoplasmic translation →+0.069+0.478.001.00339
BLOOD_LymphomaNegative regulation of myoblast fusion →+0.081+0.174<.001.00439
BLOOD_LymphomaRegulation of myoblast fusion →+0.073+0.169<.001.00438
BLOOD_LymphomaRegulation of syncytium formation by plasma membrane fusion →+0.067+0.158<.001.00829
OVARYEstablishment of protein localization to membrane →+0.038+0.419.006.00938
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,204 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by MYOZ3 expression — BLOOD_Lymphoma

Box plot of Negative regulation of syncytium formation by plasma membrane fusion in MYOZ3-low vs MYOZ3-high samples in BLOOD_Lymphoma.

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Exploration