MYOZ2

Across TCGA patient cohorts, MYOZ2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYOZ2-associated genes across cancer lineages are Monocytes, Erythrocytes, and lymphatic Endothelial cells. Each is linked with MYOZ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYOZ2-to-partner and partner-to-MYOZ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by MYOZ2-low versus MYOZ2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOZ2→partner) and Y-score (partner→MYOZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Monocytes →	+0.014	+5.305	.007	.048	3	1
UCEC	Erythrocytes →	+0.030	+3.000	.034	.037	1	2
UCEC	lymphatic Endothelial cells →	-0.028	-2.946	.043	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Monocytes by MYOZ2 expression — LIHC

Explore this box plot interactively →