MYOZ1

Across TCGA cell cohorts, MYOZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,610 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYOZ1-associated GO terms across cancer lineages are COPII-coated vesicle budding, Vesicle targeting, rough ER to cis-Golgi, and COPII vesicle coating. Each is linked with MYOZ1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MYOZ1-to-partner and partner-to-MYOZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII-coated vesicle budding grouped by MYOZ1-low versus MYOZ1-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOZ1→partner) and Y-score (partner→MYOZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	COPII-coated vesicle budding →	+0.054	+0.242	<.001	<.001	3	8
LUNG_SCLC	Vesicle targeting, rough ER to cis-Golgi →	+0.093	+0.454	<.001	.002	3	7
LUNG_SCLC	COPII vesicle coating →	+0.107	+0.503	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Autophagosome maturation →	+0.064	+0.305	<.001	.002	3	6
LARGE_INTESTINE	Secondary alcohol metabolic process →	+0.046	+0.152	.005	.008	3	6
LARGE_INTESTINE	Regulation of cardiac muscle tissue development →	+0.552	+0.151	.002	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,610 associations by consensus.

COPII-coated vesicle budding by MYOZ1 expression — CNS

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