MYOZ1

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MYOZ1 mutation is significantly associated with the drug of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYOZ1-associated genes across cancer lineages are P22077, Cytarabine, and Mirin. Each is linked with MYOZ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYOZ1-to-partner and partner-to-MYOZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P22077 grouped by MYOZ1-low versus MYOZ1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOZ1→partner) and Y-score (partner→MYOZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEP22077 →+0.465+2.649.043.04631
LARGE_INTESTINECytarabine →+0.767+2.655.049.04411
LARGE_INTESTINEMirin →+0.419+2.646.027.04711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

P22077 by MYOZ1 expression — LARGE_INTESTINE

Box plot of P22077 in MYOZ1-low vs MYOZ1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration