MYORG

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYORG mutation is significantly associated with the RNA expression of many other genes, with 4,982 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYORG-associated genes across cancer lineages are RN7SL134P, MKI67, and SAP30. Each is linked with MYORG in more than 3 cancer types. Because this analysis shows association rather than direction, both MYORG-to-partner and partner-to-MYORG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by MYORG-low versus MYORG-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYORG→partner) and Y-score (partner→MYORG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL134P →+0.149+3.704<.001.00134
COADMKI67 →+0.865+3.335<.001.00533
STADSAP30 →+0.797+3.459<.001.00533
UCECSPDL1 →+0.676+2.115<.001<.00133
UCECMCM10 →+0.789+3.021<.001<.00133
UCECRN7SL237P →+0.158+2.133.002<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,982 associations by consensus.

RN7SL134P by MYORG expression — CESC

Box plot of RN7SL134P in MYORG-low vs MYORG-high samples in CESC.

Explore this box plot interactively →

Exploration