MYORG

Across TCGA patient cohorts, MYORG mutation is significantly associated with the total protein of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYORG-associated genes across cancer lineages are ATM, FOXO3a_pS318_S321, and 14-3-3_epsilon. Each is linked with MYORG in more than 2 cancer types. Because this analysis shows association rather than direction, both MYORG-to-partner and partner-to-MYORG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by MYORG-low versus MYORG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYORG→partner) and Y-score (partner→MYORG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.712	-2.584	<.001	<.001	3	3
STAD	FOXO3a_pS318_S321 →	-0.252	-2.978	.007	.036	3	2
COAD	14-3-3_epsilon →	+0.195	+2.849	.005	.034	3	2
UCEC	Annexin-1 →	+0.468	+1.434	.007	.027	3	2
COAD	4E-BP1_pT70 →	+0.188	+2.815	.004	.036	3	2
UCEC	EGFR_pY1068 →	-0.259	-1.874	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

ATM by MYORG expression — UCEC

Explore this box plot interactively →