MYORG

Across TCGA cell cohorts, MYORG mutation is significantly associated with the RNA expression of many other genes, with 725 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYORG-associated genes across cancer lineages are KCTD17, MREG, and ULBP3. Each is linked with MYORG in more than 1 cancer types. Because this analysis shows association rather than direction, both MYORG-to-partner and partner-to-MYORG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCTD17 grouped by MYORG-low versus MYORG-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYORG→partner) and Y-score (partner→MYORG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KCTD17 →	+1.434	+3.120	<.001	.009	3	2
LARGE_INTESTINE	MREG →	+0.503	+2.244	.002	.003	3	2
LARGE_INTESTINE	ULBP3 →	+1.054	+2.850	<.001	<.001	3	2
LARGE_INTESTINE	LATS1 →	+0.544	+2.850	.002	<.001	3	2
LARGE_INTESTINE	SLC41A1 →	+0.756	+2.158	.001	.004	3	2
LARGE_INTESTINE	COPS3 →	+0.550	+2.158	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 725 associations by consensus.

KCTD17 by MYORG expression — BLOOD_Leukemia

Explore this box plot interactively →