MYOM3

Across TCGA patient cohorts, MYOM3 mutation is significantly associated with the total protein of many other genes, with 75 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYOM3-associated genes across cancer lineages are INPP4B, ATM, and FASN. Each is linked with MYOM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYOM3-to-partner and partner-to-MYOM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by MYOM3-low versus MYOM3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOM3→partner) and Y-score (partner→MYOM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.317	-2.106	.030	.018	3	4
COAD	ATM →	-0.487	-2.106	.001	.018	3	4
STAD	FASN →	+0.448	+3.185	.013	.009	3	3
STAD	Caveolin-1 →	-0.870	-3.169	.007	.017	3	3
BRCA	14-3-3_epsilon →	+0.199	+2.817	.002	.037	3	3
COAD	ASNS →	+0.416	+1.593	.007	.043	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 75 associations by consensus.

INPP4B by MYOM3 expression — COAD

Explore this box plot interactively →