MYOM3

Across TCGA cell cohorts, MYOM3 mutation is significantly associated with the RNA expression of many other genes, with 226 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYOM3-associated genes across cancer lineages are GPR101, ACP4, and ZNF644. Each is linked with MYOM3 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYOM3-to-partner and partner-to-MYOM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by MYOM3-low versus MYOM3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOM3→partner) and Y-score (partner→MYOM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GPR101 →	+0.007	+3.150	.003	.006	3	3
LUNG_SCLC	ACP4 →	+0.040	+3.765	.002	.006	3	2
LARGE_INTESTINE	ZNF644 →	+0.562	+3.364	<.001	.002	3	2
SKIN	LMO7 →	-1.142	-2.455	.009	.006	3	2
LARGE_INTESTINE	OXSM →	+0.731	+3.364	<.001	.002	3	2
LARGE_INTESTINE	C1orf52 →	+0.778	+3.364	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 226 associations by consensus.

GPR101 by MYOM3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →