Across TCGA pan-cancer cohorts, MYOM2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MYOM2 data layer compared with 23 for mass-spec protein and 9 for mutation status.
The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MYOM2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MYOM2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.
CCRCC and HNSC are the cancer types where MYOM2 mass-spec protein most reproducibly stratifies survival.