MYOM2

Across TCGA cell cohorts, MYOM2 mutation is significantly associated with the RNA expression of many other genes, with 738 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYOM2-associated genes across cancer lineages are CD300H, ZBED4, and R3HCC1. Each is linked with MYOM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYOM2-to-partner and partner-to-MYOM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by MYOM2-low versus MYOM2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOM2→partner) and Y-score (partner→MYOM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CD300H →	+0.064	+3.169	.007	.005	3	2
LARGE_INTESTINE	ZBED4 →	+0.453	+3.307	.005	.003	3	2
LARGE_INTESTINE	R3HCC1 →	+0.713	+3.459	.001	<.001	3	2
LARGE_INTESTINE	SUFU →	+0.473	+2.265	.003	.001	3	2
BLOOD_Leukemia	BVES →	+0.799	+3.459	<.001	.002	3	2
LARGE_INTESTINE	CUTC →	+0.528	+2.386	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 738 associations by consensus.

CD300H by MYOM2 expression — LUNG_SCLC

Explore this box plot interactively →