MYOM1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MYOM1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MYOM1 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher MYOM1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MYOM1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

OV and HNSC are the cancer types where MYOM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVDFSTertileAll0.6871.000.0494view →
HNSCDFSTertileIII,IV1.0000.911.0421view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MYOM1–OV (DFS)

Kaplan–Meier survival curve for MYOM1 mass-spec protein-high vs -low samples in OV.

Open the OV breakdown →

Exploration