MYOF

Across TCGA cell cohorts, MYOF RNA expression is significantly associated with the go_rna of many other GO terms, with 5,920 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYOF-associated GO terms across cancer lineages are Positive regulation of plasma membrane repair, Membrane raft assembly, and Regulation of cell-matrix adhesion. Each is linked with MYOF in more than 16 cancer types. Because this analysis shows association rather than direction, both MYOF-to-partner and partner-to-MYOF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of plasma membrane repair grouped by MYOF-low versus MYOF-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOF→partner) and Y-score (partner→MYOF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of plasma membrane repair →	+0.298	+4.638	<.001	<.001	3	17
LIVER	Membrane raft assembly →	+0.203	+4.217	.001	<.001	3	15
BONE	Regulation of cell-matrix adhesion →	+0.160	+5.081	<.001	<.001	3	15
BONE	Positive regulation of cell-matrix adhesion →	+0.169	+4.244	<.001	<.001	3	15
SOFT_TISSUE	Membrane raft organization →	+0.176	+2.664	<.001	<.001	3	15
SOFT_TISSUE	Wound healing →	+0.135	+3.431	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,920 associations by consensus.

Positive regulation of plasma membrane repair by MYOF expression — BONE

Explore this box plot interactively →