MYOD1

Across TCGA cell cohorts, MYOD1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYOD1-associated genes across cancer lineages are IFNA4, GUCY2F, and DDX25. Each is linked with MYOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYOD1-to-partner and partner-to-MYOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA4 grouped by MYOD1-low versus MYOD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOD1→partner) and Y-score (partner→MYOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNA4 →	+0.055	+4.922	<.001	.009	3	1
LARGE_INTESTINE	GUCY2F →	+0.008	+2.688	<.001	.008	3	1
LARGE_INTESTINE	DDX25 →	+0.086	+3.254	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

IFNA4 by MYOD1 expression — BLOOD_Leukemia

Explore this box plot interactively →