MYOC

Across TCGA patient cohorts, MYOC protein abundance is significantly associated with the RNA expression of many other genes, with 3,825 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MYOC-associated genes across cancer lineages are PRUNE2, PEX5L, and ST13P11. Each is linked with MYOC in more than 1 cancer types. Because this analysis shows association rather than direction, both MYOC-to-partner and partner-to-MYOC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYOC versus PRUNE2 in PDAC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOC→partner) and Y-score (partner→MYOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PRUNE2 →	-0.751	-0.864	.006	.009	3	2
LSCC	PEX5L →	-0.647	-0.353	.002	.002	3	2
PDAC	ST13P11 →	-0.737	-1.044	.002	.002	3	2
PDAC	PPIL1P1 →	-0.258	-1.038	.001	<.001	3	2
UCEC	DIPK2B →	+0.577	+0.636	.009	.004	3	2
HNSC	CORO6 →	+1.163	+0.565	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,825 associations by consensus.

MYOC vs PRUNE2 — PDAC

Explore this scatter interactively →