MYO7A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYO7A protein abundance is significantly associated with the RNA expression of many other genes, with 4,532 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MYO7A-associated genes across cancer lineages are C1orf21, PHF5A, and MEFV. Each is linked with MYO7A in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO7A-to-partner and partner-to-MYO7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO7A versus C1orf21 in CCRCC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO7A→partner) and Y-score (partner→MYO7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCC1orf21 →-0.893-0.407<.001.00333
LSCCPHF5A →-0.977-0.582.003.00232
LSCCMEFV →+0.912+0.956.001.00932
LSCCBIN2 →+1.515+0.956.002.00932
LSCCFLVCR2 →+1.053+0.956.007.00932
LSCCLILRB2 →+1.582+0.875.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,532 associations by consensus.

MYO7A vs C1orf21 — CCRCC

Per-sample scatter of MYO7A vs C1orf21 in CCRCC (Pearson r = -0.40).

Explore this scatter interactively →

Exploration