Across TCGA patient cohorts, MYO6 mutation is significantly associated with the RNA expression of many other genes, with 4,876 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO6-associated genes across cancer lineages are FDXR, SHE, and DAZAP1. Each is linked with MYO6 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYO6-to-partner and partner-to-MYO6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO6→partner) and Y-score (partner→MYO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	FDXR →	+0.616	+3.712	.004	<.001	3	4
UCEC	SHE →	-0.318	-1.563	<.001	<.001	3	4
UCEC	DAZAP1 →	+0.262	+1.938	<.001	.001	3	4
UCEC	NDUFA8 →	+0.388	+1.758	<.001	<.001	3	4
UCEC	COX5A →	+0.314	+2.010	<.001	<.001	3	4
UCEC	DIPK2B →	-0.360	-2.630	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,876 associations by consensus.

Exploration

MYO6 survival (RNA) · tumor vs normal (RNA) · all MYO6 data types