Across TCGA patient cohorts, MYO6 mutation is significantly associated with the total protein of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO6-associated genes across cancer lineages are TFRC, P-Cadherin, and c-Kit. Each is linked with MYO6 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO6-to-partner and partner-to-MYO6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO6→partner) and Y-score (partner→MYO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	TFRC →	+0.746	+3.321	.010	.010	3	3
UCEC	P-Cadherin →	-0.148	-3.321	<.001	<.001	3	3
STAD	c-Kit →	-0.300	-3.321	.043	.010	3	2
UCEC	eEF2 →	+0.326	+1.847	.001	.007	3	2
UCEC	GAPDH →	+0.352	+1.584	.018	.015	3	2
UCEC	ACVRL1 →	-0.123	-1.735	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Exploration

MYO6 survival (RNA) · tumor vs normal (RNA) · all MYO6 data types