MYO5C

Across TCGA patient cohorts, MYO5C protein abundance is significantly associated with the RNA expression of many other genes, with 15,424 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MYO5C-associated genes across cancer lineages are CRACR2B, FAM174B, and AGR2. Each is linked with MYO5C in more than 6 cancer types. Because this analysis shows association rather than direction, both MYO5C-to-partner and partner-to-MYO5C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO5C versus CRACR2B in BRCA, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO5C→partner) and Y-score (partner→MYO5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CRACR2B →	+0.867	+0.353	<.001	.001	3	7
BRCA	FAM174B →	+1.301	+0.670	<.001	<.001	3	7
BRCA	AGR2 →	+3.916	+0.713	<.001	<.001	3	6
LUAD	GLS →	-0.836	-0.398	<.001	<.001	3	6
BRCA	MLPH →	+3.005	+0.688	<.001	<.001	3	6
BRCA	TSPAN1 →	+2.384	+0.645	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,424 associations by consensus.

MYO5C vs CRACR2B — BRCA

Explore this scatter interactively →