MYO5B

Across TCGA patient cohorts, MYO5B RNA expression is significantly associated with the protein abundance of many other proteins, with 10,119 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MYO5B-associated proteins across cancer lineages are MYO5B_S1102, MYO5B_S1290, and RELCH. Each is linked with MYO5B in more than 7 cancer types. Because this analysis shows association rather than direction, both MYO5B-to-partner and partner-to-MYO5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO5B versus MYO5B_S1102 in UCEC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO5B→partner) and Y-score (partner→MYO5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYO5B_S1102 →	+1.912	+0.885	<.001	.001	3	8
GBM	MYO5B_S1290 →	+1.080	+1.304	<.001	<.001	3	8
OV	RELCH →	+0.355	+0.779	.002	<.001	3	6
HNSC	VPS4B →	+0.372	+1.232	<.001	<.001	3	5
UCEC	BSPRY →	+0.673	+0.594	<.001	.003	3	5
COAD	SMAD4 →	+0.243	+0.426	.003	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,119 associations by consensus.

MYO5B vs MYO5B_S1102 — UCEC

Explore this scatter interactively →