MYO5B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYO5B protein abundance is significantly associated with the RNA expression of many other genes, with 8,784 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MYO5B-associated genes across cancer lineages are ATP8B1, ADAD1P2, and RELCH. Each is linked with MYO5B in more than 7 cancer types. Because this analysis shows association rather than direction, both MYO5B-to-partner and partner-to-MYO5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO5B versus ATP8B1 in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO5B→partner) and Y-score (partner→MYO5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCATP8B1 →+0.971+0.573<.001<.00138
HNSCADAD1P2 →+0.984+0.553<.001<.00137
LSCCRELCH →+0.554+0.447<.001<.00136
COADRAB27B →+1.186+0.251.006.00236
HNSCLINC01269 →+1.095+0.557<.001<.00135
BRCANEDD4L →+0.849+0.507<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,784 associations by consensus.

MYO5B vs ATP8B1 — HNSC

Per-sample scatter of MYO5B vs ATP8B1 in HNSC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration