MYO3B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYO3B protein abundance is significantly associated with the RNA expression of many other genes, with 2,662 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MYO3B-associated genes across cancer lineages are EYA4, FGF1, and LTBP2. Each is linked with MYO3B in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO3B-to-partner and partner-to-MYO3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO3B versus EYA4 in LSCC, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO3B→partner) and Y-score (partner→MYO3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCEYA4 →+1.197+0.959.001.00332
CCRCCFGF1 →+1.277+1.304.002<.00132
LSCCLTBP2 →+1.273+1.164<.001.00632
LSCCRANBP3L →+1.198+1.441<.001<.00132
CCRCCFBLN1 →+1.364+1.281.003<.00132
CCRCCMOXD1 →+2.107+1.046<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,662 associations by consensus.

MYO3B vs EYA4 — LSCC

Per-sample scatter of MYO3B vs EYA4 in LSCC (Pearson r = 0.65).

Explore this scatter interactively →

Exploration