MYO3B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MYO3B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,508 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYO3B-associated GO terms across cancer lineages are Positive regulation of iron ion transport, Positive regulation of iron ion transmembrane transport, and L-ascorbic acid metabolic process. Each is linked with MYO3B in more than 6 cancer types. Because this analysis shows association rather than direction, both MYO3B-to-partner and partner-to-MYO3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of iron ion transport grouped by MYO3B-low versus MYO3B-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO3B→partner) and Y-score (partner→MYO3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERPositive regulation of iron ion transport →+1.468+0.378.001.00937
LIVERPositive regulation of iron ion transmembrane transport →+1.468+0.378.001.00937
OVARYL-ascorbic acid metabolic process →+0.099+0.929.002.00436
OVARYGeranylgeranyl diphosphate metabolic process →+0.106+1.074<.001<.00136
OVARYEstablishment or maintenance of epithelial cell apical/basal polarity →+0.114+1.279<.001.00236
STOMACHNegative regulation of mRNA catabolic process →+0.075+0.331<.001.00127
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,508 associations by consensus.

Positive regulation of iron ion transport by MYO3B expression — LIVER

Box plot of Positive regulation of iron ion transport in MYO3B-low vs MYO3B-high samples in LIVER.

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Exploration