MYO3A

Across TCGA cell cohorts, MYO3A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,854 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MYO3A-associated GO terms across cancer lineages are Aerobic electron transport chain, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with MYO3A in more than 8 cancer types. Because this analysis shows association rather than direction, both MYO3A-to-partner and partner-to-MYO3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic electron transport chain grouped by MYO3A-low versus MYO3A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO3A→partner) and Y-score (partner→MYO3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Aerobic electron transport chain →	+0.075	+0.797	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	ATP synthesis coupled electron transport →	+0.090	+0.390	.001	.006	3	9
UPPER_AERODIGESTIVE_TRACT	Mitochondrial ATP synthesis coupled electron transport →	+0.090	+0.390	.001	.006	3	9
LUNG_SCLC	Spliceosomal conformational changes to generate catalytic conformation →	+0.103	+1.568	<.001	.008	3	8
OVARY	Ribonucleoside triphosphate biosynthetic process →	+0.071	+1.091	.001	.001	3	8
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.092	+0.823	<.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,854 associations by consensus.

Aerobic electron transport chain by MYO3A expression — OVARY

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