MYO1H

Across TCGA pan-cancer cohorts, MYO1H RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MYO1H data layer compared with 8 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MYO1H RNA is associated with better overall survival. In most high-consensus cancer types, elevated MYO1H expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

HNSC, LUAD, and LGG are the cancer types where MYO1H RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.733	0.588	<.001	202	view →
LUAD	OS	Median	II,III,IV	0.783	0.635	.002	51	view →
LGG	DFS	Median	All	0.666	0.796	<.001	49	view →
ACC	DFS	Quartile	All	0.118	0.523	.005	25	view →
SCLC	DFS	Median	II,III,IV	0.500	0.199	.007	24	view →
LIHC	DFS	Quartile	All	0.435	0.621	.006	21	view →
BLCA	OS	Tertile	IV	0.234	0.696	.005	16	view →
THYM	OS	Quartile	All	1.000	0.667	.005	15	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	11	view →
KIRC	DFS	Tertile	All	0.559	0.723	.008	10	view →
BRCA	DFS	Tertile	IV	0.268	0.643	.015	9	view →
READ	DFS	Quartile	III,IV	0.306	0.807	.027	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MYO1H–HNSC (OS)

Open the HNSC breakdown →