MYO1G

Across TCGA cell cohorts, MYO1G RNA expression is significantly associated with the go_rna of many other GO terms, with 2,784 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MYO1G-associated GO terms across cancer lineages are Regulation of protein localization to endoplasmic reticulum, Negative regulation of mRNA splicing, via spliceosome, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with MYO1G in more than 8 cancer types. Because this analysis shows association rather than direction, both MYO1G-to-partner and partner-to-MYO1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to endoplasmic reticulum grouped by MYO1G-low versus MYO1G-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1G→partner) and Y-score (partner→MYO1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of protein localization to endoplasmic reticulum →	+0.139	+0.212	.005	.006	3	9
LARGE_INTESTINE	Negative regulation of mRNA splicing, via spliceosome →	+0.093	+0.258	<.001	<.001	3	8
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.122	+0.190	<.001	.002	3	8
OESOPHAGUS	Regulation of translational initiation →	+0.078	+0.178	<.001	<.001	3	8
OESOPHAGUS	Regulation of myoblast fusion →	+0.126	+0.190	<.001	.002	3	8
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.134	+0.165	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,784 associations by consensus.

Regulation of protein localization to endoplasmic reticulum by MYO1G expression — OESOPHAGUS

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