MYO1F

Across TCGA pan-cancer cohorts, MYO1F mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated MYO1F data layer compared with 23 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MYO1F mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MYO1F expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

COAD, UCEC, and PDAC are the cancer types where MYO1F mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	III,IV	0.815	1.000	.016	66	view →
UCEC	OS	Median	II,III,IV	1.000	0.628	.013	18	view →
PDAC	DFS	Median	All	0.578	0.859	.008	15	view →
HNSC	DFS	Tertile	All	1.000	0.623	.040	6	view →
GBM	OS	Quartile	All	0.399	0.690	.010	3	view →
LUAD	DFS	Median	All	0.726	0.504	.045	2	view →
LSCC	DFS	Median	II,III,IV	0.572	0.823	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

MYO1F–COAD (DFS)

Open the COAD breakdown →