MYO1F

Across TCGA cell cohorts, MYO1F mutation is significantly associated with the RNA expression of many other genes, with 199 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYO1F-associated genes across cancer lineages are RFC5, PLAC8, and VWC2. Each is linked with MYO1F in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO1F-to-partner and partner-to-MYO1F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFC5 grouped by MYO1F-low versus MYO1F-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1F→partner) and Y-score (partner→MYO1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RFC5 →	+0.770	+3.351	.001	.003	3	2
BLOOD_Leukemia	PLAC8 →	-2.652	-3.292	.001	.007	3	2
OESOPHAGUS	VWC2 →	+0.064	+3.857	<.001	.002	3	1
OESOPHAGUS	C18orf63 →	+0.005	+3.392	<.001	.007	3	1
OESOPHAGUS	PAPOLB →	+0.031	+3.836	<.001	.004	3	1
BLOOD_Lymphoma	FCN2 →	+0.036	+5.129	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 199 associations by consensus.

RFC5 by MYO1F expression — BLOOD_Leukemia

Explore this box plot interactively →