MYO1E

Across TCGA cell cohorts, MYO1E mutation is significantly associated with the RNA expression of many other genes, with 313 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYO1E-associated genes across cancer lineages are RBMY1F, IFNA4, and CGB2. Each is linked with MYO1E in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO1E-to-partner and partner-to-MYO1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1F grouped by MYO1E-low versus MYO1E-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1E→partner) and Y-score (partner→MYO1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RBMY1F →	+0.221	+4.887	<.001	.009	3	2
BLOOD_Myeloma	IFNA4 →	+0.033	+4.807	<.001	.006	3	1
BLOOD_Leukemia	CGB2 →	+0.796	+3.556	<.001	.001	3	1
BLOOD_Leukemia	RLN1 →	+0.464	+3.518	<.001	.008	3	1
BLOOD_Leukemia	PHOX2B →	+0.016	+3.365	<.001	.005	3	1
BLOOD_Leukemia	ART4 →	+0.725	+3.708	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 313 associations by consensus.

RBMY1F by MYO1E expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →