Across TCGA patient cohorts, MYO1C mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO1C-associated genes across cancer lineages are PDCD4, NDRG1_pT346, and EGFR_pY1068. Each is linked with MYO1C in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO1C-to-partner and partner-to-MYO1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1C→partner) and Y-score (partner→MYO1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PDCD4 →	-0.555	-2.991	.011	.036	3	2
SKCM	NDRG1_pT346 →	-0.734	-3.000	.032	.035	3	2
UCEC	EGFR_pY1068 →	-0.243	-2.263	.003	<.001	3	2
UCEC	STAT3_pY705 →	-0.308	-1.574	<.001	.017	3	2
UCEC	ATM →	-0.409	-2.687	.006	.005	3	2
COAD	Lck →	+0.508	+3.025	.001	.019	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

MYO1C survival (RNA) · tumor vs normal (RNA) · all MYO1C data types